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Medicines that inhibit CYP2D6 activity, such as paroxetine and quinidine, may cause reduced clearance of oxycodone which may lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.Breastfeeding Administration to nursing Ladies will not be

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